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Fluticasone; Umeclidinium; Vilanterol inhalation powder

What is this medicine?

FLUTICASONE; UMECLIDINIUM; VILANTEROL (floo TIK a sone; ue MEK li DIN ee um; vye LAN ter ol) inhalation is a combination of 3 drugs to treat COPD and asthma. Umeclidinium and Vilanterol are bronchodilators that help keep airways open. Fluticasone decreases inflammation in the lungs. Do not use this drug combination for acute asthma attacks or bronchospasm.

How should I use this medicine?

This drug is inhaled through the mouth. Rinse your mouth with water after use. Make sure not to swallow the water. Take it as directed on the prescription label at the same time every day. Do not use it more often than directed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician about the use of this drug in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash or hives, swelling of the face, lips, or tongue

  • breathing problems right after inhaling your medicine

  • chest pain

  • eye pain

  • fast, irregular heartbeat

  • feeling faint or lightheaded, falls

  • fever or chills

  • nausea, vomiting

  • signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.

  • trouble passing urine

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • changes in taste

  • cough

  • diarrhea

  • headache

  • nervousness

  • sore throat

  • tremor

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • cisapride

  • dofetilide

  • dronedarone

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • pimozide

  • thioridazine

  • ziprasidone

This medicine may also interact with the following medications:

  • aclidinium

  • antihistamines for allergy

  • antiviral medicines for HIV or AIDS

  • atropine

  • beta-blockers like metoprolol and propranolol

  • certain antibiotics like clarithromycin and telithromycin

  • certain medicines for bladder problems like oxybutynin, tolterodine

  • certain medicines for depression, anxiety, or psychotic disturbances

  • certain medicines for fungal infections like ketoconazole, itraconazole, posaconazole, voriconazole

  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl

  • certain medicines for stomach problems like dicyclomine, hyoscyamine

  • certain medicines for travel sickness like scopolamine

  • conivaptan

  • diuretics

  • ipratropium

  • medicines for colds

  • other medicines for breathing problems

  • other medicines that prolong the QT interval (cause an abnormal heart rhythm)

  • nefazodone

  • tiotropium

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep inhaler away from extreme heat, cold or humidity. Throw away 6 weeks after removing it from the foil pouch, when the dose counter reads "0" or after the expiration date, whichever is first.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bone problems

  • diabetes

  • eye disease, vision problems

  • heart disease

  • high blood pressure

  • history of irregular heartbeat

  • immune system problems

  • infection

  • kidney disease

  • pheochromocytoma

  • prostate disease

  • seizures

  • thyroid disease

  • trouble passing urine

  • an unusual or allergic reaction to fluticasone, umeclidinium, vilanterol, lactose, milk proteins, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checkups. Tell your doctor or health care professional if your symptoms do not get better. Do not use this medicine more than once every 24 hours.

NEVER use this medicine for an acute asthma or COPD attack. You should use your short-acting rescue inhalers for this purpose. If your symptoms get worse or if you need your short-acting inhalers more often, call your doctor right away.

If you are going to have surgery tell your doctor or health care professional that you are using this medicine. Try not to come in contact with people with the chicken pox or measles. If you do, call your doctor.

This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.

Author: StayWell Custom Communications
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