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Erdafitinib tablets

What is this medicine?

ERDAFITINIB (ER da FI ti nib) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat urothelial cancer.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. You can take it with or without food. If it upsets your stomach, take it with food.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • blurred vision

  • changes in vision

  • signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine

  • signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • constipation

  • diarrhea

  • dry eyes

  • dry mouth

  • loss of appetite

  • nausea

What may interact with this medicine?

This medicine may interact with the following medications:

  • antiviral medicines for HIV or AIDS

  • certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, and voriconazole

  • certain medicines for seizures like carbamazepine, phenobarbital, and phenytoin

  • clarithromycin

  • conivaptan

  • cyclosporine

  • digoxin

  • enzalutamide

  • grapefruit or grapefruit juice

  • idelalisib

  • mitotane

  • nefazodone

  • rifampin

  • St. John's Wort

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children. Store between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • eye disease, vision problems

  • high levels of phosphorous in the blood

  • an unusual or allergic reaction to erdafitinib, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your vision and blood may be tested before and during use of this medicine.

Tell your doctor or health care professional right away if you have any change in your eyesight.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

Do not become pregnant while taking this medicine or for 1 month after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 1 month after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 1 month after stopping it.

This medicine may interfere with the ability to have a child. Talk with your doctor or health care professional if you are concerned about your fertility.

Author: StayWell Custom Communications
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