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Onasemnogene Abeparvovec suspension for injection

What is this medicine?

ONASEMNOGENE ABEPARVOVEC (ON a SEM noe jeen A be PAR voe vek) is used to treat patients with spinal muscular atrophy (SMA). It is not a cure.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as newborns for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives; swelling of the face, lips, or tongue

  • signs and symptoms of infection like fever; chills; cough; sore throat

  • signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin

  • unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • vomiting

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

This does not apply. This medicine is not for regular use.

Where should I keep my medicine?

This medicine is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease

  • liver disease

  • low blood counts, like a low platelet count

  • an unusual or allergic reaction to onasemnogene abeparvovec, other medicines, foods, dyes or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. You will need blood work done while you are taking this medicine.

This medicine may be present in urine and stool. Special care for handling body waste, trash, laundry, spills, and family interactions may be needed. Talk to your healthcare professional about how to protect yourself and family.

Author: StayWell Custom Communications
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